Biotechnology in Healthcare and Medicine

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Biotechnology in Healthcare and Medicine: Overview

This Topic covers sub-topics such as ELISA, Adenosine deaminase Deficiency, Genetically Engineered Insulin, Biotechnology in Medicine, Molecular Diagnosis of Diseases and, Gene Therapy

Important Questions on Biotechnology in Healthcare and Medicine

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The use of DNA as a pharmaceutical agent to treat disease is called:

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Deficiency of the enzyme ADA causes:

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Which of the following protein has been produced by methods of genetic engineering?

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Which of the following types of ELISA contain the following steps?

Antigen binding, Blocking, Primary antibody, Secondary antibody, Enzyme-linked antibody, Substrate, Colorimetric reading (Represented in diagram).

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Human protein α-1 - anti trypsin is used to treat which disease?

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Statement-I: ELISA is based on the principle of antigen-antibody interaction.
Statement-II: Infection by pathogens can be detected by the presence of antigens or by detecting the antibodies synthesised against the pathogens.

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Read the following statements and select the correct option from below:

I. Genetically modified crops are more susceptible to natural stress conditions like drought, salinity, etc., as compared to normal crops

II. For the treatment of ADA (adenosine deaminase) deficiency treatment, a functional ADA cDNA was introduced to the lymphocytes of the patient by using lambda phage virus

III. There are more than 3,00,000 rice varieties in India alone

IV. Nitrates, phosphates are easily removed from polluted water in the water treatment plant.

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In the PCR technique during the detection of the mutated gene, a single-stranded DNA or RNA, tagged with a radioactive molecule is allowed to hybridise to its complementary DNA in a clone of cells followed by detection using autoradiography. In this statement which of the following term can be used as “radioactive molecule”?

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Which of the following is an incorrect statement?

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Match Column I with Column II and select the correct option.

  Column I   Column II
A. Rhizobium i) Production of human insulin
B. Bacillus thuringiensis ii) Production of Bt toxin
C. Escherichia coli iii) Scavenging of oil spills
D. Pseudomonas putida iv) Nif gene

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The first clinical gene therapy was done for treatment of

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The polymerase chain reaction (PCR) is used to

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The two short polypeptide chains: chain A and chain B in insulin are linked together by:

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At present about ______ recombinant therapeutics have been approved for human use the world over and _______ of these are presently marketed in India.

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The first clinical gene therapy was given in __(i)__ to a __ (ii) __ year old girl with __ (iii) __ deficiency. Fill in the blanks with the correct option.
 

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During the processing of the prohormone, proinsulin converted into the mature insulin by,